InnovationWell Interaction Meeting: Nov 21, Basel

A New Era in Using Natural Products for Drug Development and Health

Event Program: 

  • 14.30 Welcome and Networking, Coffee and Cakes
  • 15.00 Perspectives (10 minutes each)
  • 15.40 Panel Discussion
  • 16.00 Knowledge Cafe discussions in groups
  • 17.00 Social Reception
  • 18.00 End of event

Further Perspectives

Progressing Data Sharing on Natural ProductsTimea Polgar, Founder and CEO, Envision Biotechnology

How could modern technology and recent crowdsourcing approaches support the data sharing of complex information on natural products? Information on natural products and traditional medicine is often ambiguous or unavailable and current databases may not be applicable broadly for discovery sciences. Therefore, there is an unmet need for standardized and structured databases with a wide scope covering: natural product sources, their chemistry, and in vitro, in vivo and traditional data.

Supporting Evaluation and Decision-making in Natural Product Innovation, Barry Hardy, CEO, Douglas Connect and President, OpenTox Association

Over the past decade, OpenTox has motivated a global community of scientists sharing data, knowledge and best practices related to toxicology. Today, the open knowledge standards ideas of OpenTox are being implemented within OpenRiskNet to support the safety assessment goals of chemicals. Within the BaselArea DayOne initiative in Precision Medicine, we are extending infrastructure applications to trusted precision medicine, supported by blockchain technology. Within NanoCommons, we are extending these applications to the evaluation of complex Nano Materials and Nano Medicine. How can we tackle the problem of Natural Products? How can we aid the needed data sharing, the integrated testing and safety assessment, the challenges of complex molecules, the uncertainties in modelling mixtures? Let’s put our heads together and see what problems we can solve! Our best ideas should lead to actions supporting the Natural Product development goals of providing health, environmental and business benefits.

Challenges and solutions in high-throughput screening of natural products, David Bruno, Director Natural Substances, R&D Sourcing & Botany at Pierre Fabre Research Institute

There are some 300,000 natural products available today; however, only 10% of these compounds are physically available for testing. How can crowdsourcing help test more natural products? Could a network of natural product scientists form a supply chain to test natural products? What could be the benefits and challenges for discovery scientists?

Challenges and possible solutions on patentability of natural products. A case study from Africa, Philip Judson, Founder, Lhasa Limited

Natural products cannot be patented, this is one reason why drug discovery scientists turned away from the frequent application of natural products. However, there are several ways that IP and related business challenges can be managed. An African story will provide further insights on how natural products could be involved in modern research workflows.

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