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Knowledge Management in R&D
optimising productivity in knowledge creation,
capture, retrieval and transfer |
InterAction Meeting Session, held in Philadelphia, USA, 12 October 2005
chaired by Herschel J Weintraub (CambridgeSoft) |
Presenters and Discussion Leaders:
The ABCD Project, a Framework for Knowledge Management, Peter Gates (Johnson and Johnson)
Enabling Collaboration in a Virtual and Global Drug Discovery R&D Environment : Collaboration- it doesn’t just "happen", John Barrett, Principal (ITI Associates)
Global Information Integration in R&D, Scott Starry, Senior Product Manager (Symyx IntelliChem)
Knowledge Management Case Study Analysis of a Collaborative Life Science R&D Environment, Jeff Spitzner, CSO (Rescentris)
An Interactive Environment for Multiparameter Optimization and Knowledge Management, James H Wikel, CTO (Coalesix)
Measuring Knowledge Management via Social Network Analysis, Bonnie Montano (Georgetown University)
Natural Language Processing for Knowledge Extraction in the Life Sciences, Rosemary Polsky-Newman, VP, Corporate Development (ExerGen Biosciences)
Managing Knowledge in Breast Cancer: Converting Clinical, Molecular and Imaging Data into Knowledge, Michael Liebman (Windber Research Institute)
Legal Issues in a Knowledge Sharing Environment, James M. Kanagy, Director e-Commerce and Business Method Patents (GlaxoSmithKline)
Analysis based on Molecular Diversity, Steve Boyer (IBM)
| InterAction Meeting Session, held in Basel, Switzerland, 9 November 2005
chaired by Robert Scoffin (CambridgeSoft)
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Presenters and Discussion Leaders:
ABCD and Combinatorial Library Design, Alan Gibbs (Johnson and Johnson)
Assembly, Distribution and Retrieval of Biological Information in Drug Discovery, Kim Henrick, Macromolecular Structure Database (MSD) group leader (European Bioinformatics Insititute)
Molecular Architecture to Prepare Structures with Desired Properties: The Integration of Databases and Software into the Day-to-Day Practice of a Medicinal Chemist, Ulrich Jordis (Vienna University of Technology)
Ontologies: Real Applications in Pharma, Steve Gardner, CTO (Biowisdom)
Pharmaceutical Development and the use of Electronic Lab Notebooks, Michael Swartz, VP, Knowledge Management (CambridgeSoft)
Global Information Integration in R&D, Pierre Allemand, Director, Business Development (Symyx AG)
Strategic Knowledge Management in Life Science Research, Victor Newman (The Knowledgeworks)
Aggregation, Filtering and Alerting of Scientific Information from Multiple Sources, Mark Sharp (Corpora)
Global Roll Out of an Electronic Notebook at Schering AG, Rolf Jautelat (Schering AG)
Knowledge Management Methodologies and Auditing for Electronic Lab Notebook Implementations, Barry Hardy (Douglas Connect) and Jeff Spitzner (Rescentris)
A Conceptual Look at Online Collaboration, Christoph Seitz (Colayer) |
Innovation, as driven by the creation of new knowledge in research and development, and its accelerated deployment into products and services on the market, is a key strategic goal of the R&D organisation. The evolving field of knowledge management provides both important strategic components and a diverse, growing toolkit of tactical measures, methodologies and technologies that can be integrated into the continuous improvement of the organisation’s performance and supporting systems, so as to gain sustainable competitive advantage.
Supporting systems for the scientific researcher such as electronic lab notebooks and collaborative eR&D systems are increasingly being used to replace paper-based systems in the recording and capture of laboratory information on research and experiments. These systems need to be designed to support the needs of the researcher in their day-to-day working processes, to support knowledge-sharing between researchers and between research groups and other functions in the organisation, in addition to meeting regulatory, intellectual property and legal requirements. Electronic records in these systems must satisfy legal record retention, usability and authenticity requirements. Experimental records including documents, diverse scientific data types, analyses, annotations, and reports, plus metadata that relate authorship, date stamps, digital signatures, and other information, can be captured in systems, which need to support current and future integration, querying and mining of the data.
New knowledge-based technologies in natural language processing, search, classification, ontologies and the semantic web are additionally providing new tools for the enhancement of the productivity of the researcher and in the enabling of the asking and more timely answering of powerful questions.
User adoption of new systems, cultural issues, organisational learning, communities of practice and collaboration are also all key areas requiring attention to maximise value extraction and return on research investment. Knowledge transfer and flow between different research groups within the organisation and with an increasing number of partners needs to be enhanced by knowledge process management. Finally the transfer of knowledge to and from other parts of the business (clinical, marketing etc.) and across the complete product life cycle provides many challenges to which best knowledge management practices may contribute.
Issues addressed by this program are as follows:
• Knowledge Management as a strategy for R&D and innovation processes
• Knowledge transfer and flow within and without R&D
• Personal Knowledge Management and Productivity of the Scientific Researcher
• Role of Collaborative R&D and Communities of Practice in Life Science Research
• Conducting a Knowledge Audit of your R&D organisation and integrating findings into your research processes and systems
• Transfer of Knowledge to and from R&D and other Organisational Functions (clinical, marketing etc.)
• Effective Classification and Indexing of Laboratory Knowledge
• Enabling the Asking and Answering of Scientific Questions
• Applying Advanced Search Techniques, Natural Language Processing, Agents to Secondary Research and the processing and access to new knowledge
• Applying Knowledge Management Mapping and Metrics to R&D
• Challenges, benefits and investment analysis from Case studies
• Managing the transition to mixed paper-electronic and electronic-only approaches
• Best practice and Standard Operating Procedures for electronic record-keeping
• Integration of laboratory data into the global knowledge environment
• Pros and cons of centralisation and localisation
• Creativity and intuition, how do we best support novel ideas and innovating?
• How do we make collaborative virtual work environments for R&D work?
• Usability and retrieval of electronic data
• Embedding knowledge into working processes and workflows
• Enabling the understanding of knowledge for groups distributed in space, time and expertise domain
• Data-sharing and analysis between remote team members
• Management of multi-site, multi-organizational collaborative projects including data management in contract and outsourced R&D projects
• FDA compliance in electronic R&D systems, 21CFR-11
• Planning for future trends in the regulatory environment
• International similarities and differences regarding keeping, managing, and submitting electronic records for IP/patents, drug approvals for FDA and equivalents
• Legal guidelines, practical experiences, law/legal case studies relating to use/acceptance (or not) of electronic records and submissions
• Reports on rates of adoption of electronic record-keeping and submissions by industry, regulatory body, and country, and other details on accepted practices, and review of audits/validation
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